Nuffield Health

The economic burden of hypertension in Sub-Saharan Africa: a systematic literature review

Abstract Background Quantifying the economic burden of disease is vital for informing healthcare resource allocation and priority setting particularly in Sub-Saharan Africa (SSA) where the incidence of non-communicable diseases (NCDs) is rising among the region’s predominantly yo...

Developing attributes and attribute-levels for a discrete choice experiment on preference for primary healthcare providers among urban slum dwellers in Bangladesh

Abstract Background Due to rapid urbanization, in many low- and middle-income countries (LMICs), urban primary healthcare (PHC) systems are not compatible with meeting the growing need for healthcare services. However, limited research exists on what patients consider important w...

Disaster Risk Management Approaches: Strategic Interventions to Revive a Devastated Health System in a Post-conflict or Disaster Setting

When struggling health systems in low- and middle-income countries, especially in African settings, further encounter armed conflicts or disasters, the overwhelmed health systems are brought to ruins. Disaster risk management (DRM) has different approaches to addressing this issu...

Antihypertensive Treatment and Risk of Metabolic Associated Fatty Liver Disease: A Drug-Target Mendelian Randomization

BACKGROUND: Metabolic dysfunction-associated fatty liver disease, conventionally known as nonalcoholic fatty liver disease (NAFLD), affects over a quarter of the global population and lacks approved pharmacological treatments. We investigated whether elevated blood pressure (BP)...

Phenomic profiles and disease patterns of 1.9 million participants from Our Future Health

Abstract Our Future Health is a prospective study aiming to recruit 5 million UK-resident adults to enable discovery and translation of disease prevention, detection and treatment approaches. So far, more than 2.5 million have enrolled, and baseline phenotypic data are available...

Advances in small area population estimation in the absence of national census data

Population data at small area scales are essential for effective decision-making, influencing public health, disaster response, and resource allocation, among others. While national censuses remain the cornerstone of population data, they are often constrained by high costs, infr...

Iron deficiency testing among people with incident heart failure in primary care

Background Given around 50% of people with heart failure have a degree of iron deficiency, guidelines recommend screening. It is uncertain to what extent this is done in primary care and whether testing is equitable. Aim To report the proportion of people with incident heart fail...