Norwich Research Park

ZPY-CpG-Ch, a broad coverage vaccine against Streptococcus pneumoniae

Existing licensed pneumococcal vaccines, including Prevnar-13 and its higher-valency successors, have played a major role in reducing invasive pneumococcal disease worldwide. However, their effectiveness is increasingly threatened by the rise of multidrug-resistant strains and th...

Whole genome comparative analysis shows limited Escherichia coli co-occurrence within co-habiting humans and dogs

Abstract Background Dogs are one of the most popular companion animals in the UK, with an estimated 13.5 million within UK households. Within these households, human-animal physical interactions may lead to inter-species bacterial sharing, including Escherichia coli . E. coli is...

Wheat genotypic variation in root architecture modifies soil pore structure and hydraulic properties

Root-driven modification of soil hydraulic properties may influence crop water availability and resilience under climatic variability, yet genotype-specific effects on rhizosphere hydrology remain poorly understood. This study examined how contrasting root architectures of four w...