NOAA National Marine Fisheries Service Southwest Fisheries Science Center

The distribution of fitness effects of nonsynonymous mutations varies phylogenetically across animals

The distribution of fitness effects (DFE) describes the selection coefficients of newly arising mutations and fundamentally influences population genetic processes. However, the extent and mechanisms of differences in the DFE for non-synonymous mutations have not been systematica...

Thermal bottlenecks constrain early-life survival of native fish in regulated rivers

Climate change is reshaping thermal regimes worldwide, threatening species whose early development depends on narrow temperature ranges. Yet directly linking warming to reproductive failure in wild populations remains intractable, particularly in aquatic ecosystems. We developed...