Institution
Nippon Medical School
Recent research
- Health & MedicineOpen access
Myofibroblast differentiation is a pivotal event in idiopathic pulmonary fibrosis (IPF) and is driven by TGF-β1–dependent PTEN destabilization; however, the intermediate regulators remain incompletely defined. We tested three lung fibroblast cell lines (one normal and two IPF-der...
- BiologyOpen access
Hematopoietic stem cells (HSCs) constitute an organized hematopoietic system that undergoes age-related alterations, including increased platelet production and decreased erythropoiesis. The fundamental mechanisms driving these shifts remain incompletely understood. We used singl...
- Health & Medicine
Background and Aims This study aimed to investigate the associations between SNPs in CPA1, GGT1, and SPINK1 genes and the clinical characteristics of refractory FD including clinical symptoms, pancreatic enzyme abnormalities, and exocrine pancreatic function.Methods 97 Patients w...
- Health & Medicine
Aims: Forefoot deformities are common in patients with rheumatoid arthritis (RA) and often impair quality of life. Patient-reported outcome measures (PROMs), including the Self-Administered Foot Evaluation Questionnaire (SAFE-Q), are increasingly used to assess surgical outcomes;...
- Health & MedicineOpen access
Femoral artery pseudoaneurysm is a known complication of arterial access, and its management can be particularly challenging in patients with severe coagulopathy or complex vascular anatomy. Here, we report a case of a giant femoral artery bifurcation pseudoaneurysm arising from...