Ningxia Center for Diseases Prevention and Control

Genetic diversity, drug resistance, and molecular transmission networks of HIV-1 in Zunyi: implications for precision prevention

Abstract Background HIV-1 genetic diversity and the spread of pretreatment drug resistance (PDR) complicate epidemic control. Southwestern China has a heterogeneous HIV epidemic, but molecular transmission dynamics in many prefecture-level settings remain poorly described. Method...

Climate change reshapes the potential transmission risk of human alveolar and cystic echinococcosis in western China: a projection based on MaxEnt models

BACKGROUND: Echinococcosis, a severe zoonotic parasitic disease, imposes a significant health burden in western China, primarily as alveolar (AE) and cystic (CE) forms caused by Echinococcus multilocularis (Em) and E. granulosus sensu lato (Egsl), respectively. Its transmission,...

Comparative genomics of the streptococcal mobilome reveals class-specific integration, mobility and antimicrobial resistance cargo

Abstract Mobile genetic elements (MGEs) drive genome plasticity, horizontal gene transfer, and antimicrobial resistance (AMR) dissemination in Streptococcus , yet genus-wide comparisons across major MGE classes remain limited. Here, we analyzed 1,961 complete genomes from 60 Stre...

Health utility and equity-related correlates among adults with rare diseases in Foshan City, China: an exploratory cross-sectional study using the EQ-5D-5L

Rare diseases (RDs) are associated with substantial and potentially avoidable health inequities related to chronic disability, social disadvantage, and high non-medical costs. Evidence on health-related quality of life (HRQoL) among adults living with RDs in China remains scarce,...