Nilai University

Ferroptosis and Iron Dyshomeostasis as Drivers of Wound Chronicity in Diabetic Foot Ulcers: Pathophysiological Mechanisms and Targeted Therapeutic Strategies

Background diabetic foot ulcers (DFUs) carry 5-year mortality rates of 50%–70% and recurrence rates of 65% at three to five years. Standard-of-care protocols fail to resolve wound chronicity in a substantial proportion of patients, reflecting incomplete understanding of the cellu...

Characterisation of monocyte migration potential in response to stimuli from human arthroplasty revision xenograft transplanted in a NOD-SCID mouse model

Monocyte migration into periprosthetic tissue in response to wear debris-induced inflammation factors (WDIF) has been identified as one of the primary contributors to the progression of osteolysis in aseptic loosening (AL) of arthroplasty implants. However, the dynamics of monocy...

A hybrid machine learning framework using fractional order dynamics to predict fish toxicity in aquatic ecosystems

Accurate prediction of chemical toxicity to aquatic organisms remains a critical challenge in environmental risk assessment. Traditional machine-learning (ML) models capture static correlations but cannot represent time-dependent, memory-driven processes such as bioaccumulation a...