Institution
Nikon (United States)
Recent research
- Engineering & Technology
A simple reverse current blocking circuit
When the direction of system current is opposite to the normal operating direction, it is called reverse current. Causes include reverse battery connection, multiple power supply parallel connection, the car starting process, etc. For example, in a battery application, if the bat...
- Materials & EnergyOpen access
Abstract Two pentacoordinate Mn(II) complexes containing tridentate 2.2′-[oxybis(methylene)] bis(1H-1,3-benzimidazole) (OMeBB) ligand and pseudohalide coligands, [Mn(OMeBB)(NCS)2] (1) and [Mn(OMeBB)(NCO)2] (2), exhibit a very rare {MnIIN4O} coordination mode involving semicoordin...
- Biology
PhenoDEL: A NovelScreening Strategy Based on IntracellularProtein Degradation Activity
Abstract Targeted protein degradation (TPD), including proteolysis targeting chimeras (PROTACs) and molecular glue degraders (MGDs), is a promising therapeutic approach. However, systematic discovery of such small molecules remains a major challenge. Here, we present PhenoDEL, a...