NIHR Moorfields Biomedical Research Centre

Three-year outcomes of combined surgical peripheral iridectomy, goniosynechialysis and goniotomy for advanced primary angle-closure glaucoma: a multicentre study

Aims To assess the 3-year efficacy and safety of combined surgical peripheral iridectomy (SPI), goniosynechialysis (GSL) and goniotomy (GT) for advanced primary angle-closure glaucoma (PACG) without cataract. Methods This was a multicentre prospective observational study with ext...

Visual crowding in infantile idiopathic nystagmus is not reduced by differences in target-flanker elements

Foveal vision in individuals with infantile idiopathic nystagmus syndrome (IINS) is impaired by reduced acuity and elevated crowding (the disruption in object recognition from clutter). In typical peripheral vision, acuity can be improved by temporal variations (flicker), while c...

OphthoEvidence Report: Comparative effects of treatments for geographic atrophy secondary to age-related macular degeneration: A protocol for a living systematic review and network meta-analysis

Background Geographic atrophy (GA), an advanced form of age-related macular degeneration (AMD), leads to legal blindness in approximately 16% of affected individuals within 6 years. Numerous trials have evaluated interventions to slow GA progression, and many studies are ongoing....