NIHR Bristol Biomedical Research Centre

Teachers’ perceptions of physical activity in children and young people with type 1 diabetes: a qualitative systematic review protocol

Abstract Background Type 1 diabetes is a lifelong condition usually diagnosed in childhood. It requires daily management to control blood glucose and avoid complications. Physical activity brings important physical and emotional benefits, but children with the condition are often...

Effects of maternal and paternal smoking on offspring cardiometabolic risk factors in adulthood: a multi-method intergenerational Mendelian randomization study

Abstract Background Parental smoking has been linked to several adverse offspring cardiometabolic outcomes; however, evidence is conflicting regarding the causal and long-term nature of these associations. Methods We investigated the effects of maternal and paternal smoking, capt...

Glucagon-like peptide-1 receptor agonists are associated with improved 90-day outcomes after total hip and knee arthroplasty

Aims Obesity and diabetes are risk factors for developing osteoarthritis and associated with worse outcomes following total hip (THA) and total knee arthroplasty (TKA). Glucagon-like peptide-1 receptor agonists (GLP-1as) improve glycaemic control and promote weight loss. The aim...