Neurobehavioral Research (United States)

HIV and anticholinergic burden: Towards a pragmatic stewardship algorithm

Abstract Background Multimorbidity and polypharmacy increase exposure to medications with anticholinergic properties in people with HIV. In elderly people, higher anticholinergic burden (ACB) is linked to cognitive impairment, falls, functional decline and mortality, whose risk i...

Sex-modulated associations between cytomegalovirus cell-associated DNA and cognition in people with HIV on ART

Background: People with HIV (PWH) remain at risk for cognitive impairment, despite effective antiretroviral therapy (ART), a phenomenon linked to chronic immune activation and inflammation. Cytomegalovirus (CMV) has been implicated in HIV-associated neurocognitive impairment, but...