Nepal Medical College Teaching Hospital

Reducing Peripheral Intravenous Catheter Use in Adult Acute Care: A Systematic Review

ABSTRACT Peripheral intravenous catheters (PIVCs) are the most frequently inserted invasive device in acute care, yet up to 52% remain unused, exposing patients to avoidable risks and increasing healthcare costs. Despite growing awareness of inappropriate PIVC use, unnecessary in...

Nutcracker syndrome with pelvic congestion syndrome: A case report

Nutcracker syndrome is a rare clinical entity characterized by external compression of left renal vein (LRV) disturbing the outflow of blood into inferior venacava. We present a case of a 35-year-old female who presented to gynecology outpatient department (OPD) with abdominal pa...

Fish bone-induced pyogenic liver abscess via contained duodenal perforation managed surgically: a case report

Pyogenic Liver Abscess (PLA) due to a foreign body (ingestion of fish bone) migration is very rare in occurrence. The diagnosis is usually delayed because the patient has difficulty remembering the history of foreign body ingestion. 44 year old male with immunocompetence presenti...

Displaced people and kidney health

Purpose of review The number of displaced people worldwide continues to rise because of conflict and disasters-related crises. Kidney disease is increasingly recognized as an important contributor to morbidity among displaced populations, yet it remains under-prioritized in human...

Neuropeptide Alterations in Type 2 Diabetes Mellitus: A Meta‐Analysis of Circulating Spexin and Galanin Levels

ABSTRACT Background Spexin and galanin are neuropeptides involved in glucose homeostasis, insulin sensitivity, appetite, and energy metabolism. We conducted a systematic review and meta‐analysis to synthesise evidence on circulating spexin and galanin concentrations in patients w...

Morphology-based screening for sickle cell disease using low-cost automated microscopy and machine learning

Abstract Sickle cell disease (SCD) and β-thalassemia are the most common monogenic diseases, disproportionately affecting low- and middle-income countries, where low-cost and accurate diagnostic tools are needed to reduce the global disease burden. Although the sickling test is c...