National Tsing Hua University

Sfp1 Contributes to Fluconazole Responses and Virulence in Candida albicans

Candida albicans is an important human fungal pathogen. Previous studies have shown that the transcription factor Sfp1 is involved in regulation of various biological processes in C. albicans, including cell wall maintenance, biofilm formation, oxidative stress responses, and car...

Carotid energy pulsatility index provides complementary hemodynamic information to renal function in a community-based cohort

Abstract Conventional hemodynamic, including Carotid–femoral pulse wave velocity (cfPWV), characteristic impedance (Zc), and brachial pulse pressure, do not directly quantify pulsatile energy transmission through the arterial system. Carotid energy pulsatility index (PI), derived...

Supporting Socialization Skills of Preschoolers with Developmental Delays in Inclusive Education: An Early-Career Teacher’s Implementation of Curriculum Modifications

This practitioner action research examined how an early-career preschool teacher implemented Building Blocks–informed curriculum modifications to support the socialisation-related IEP goals of two children with developmental delays in an inclusive public preschool in Taiwan. Clas...

Computationally Guided Design of Facet-Defined Multielement Active Sites on Hexagonal Close-Packed High-Entropy-Alloy Nanosheets for Alkaline Hydrogen Evolution

Abstract Nonconventional hexagonal close-packed (HCP) high-entropy alloys (HEAs) provide distinct catalytic surfaces, but their synthesis with well-defined facets remains challenging, leaving facet-dependent multielement ensemble effects largely unexplored. Here, we report the co...

Crowding‐driven condensation and membrane reorganization

Abstract Although biological membranes exhibit complex and dynamic organization, the mechanistic role of molecular crowding in governing lateral membrane heterogeneity remains poorly characterized experimentally. Here, we provide direct experimental visualization showing that cro...

Coordination‐Asymmetry‐Regulated Reconstruction of Electron‐Rich Cu Sites for pH‐Dependent Nitrate‐to‐Ammonia Electrocatalysis

ABSTRACT Electrocatalytic nitrate reduction reaction ( e‐ NO 3 RR) offers a promising route to valorize nitrate‐contaminated wastewater while enabling sustainable ammonia production; however, how local coordination asymmetry regulates Cu‐site evolution and reaction pathways acros...

Metal Active‐Site Engineering in High‐Entropy Catalysts for Catalytic Applications

High-entropy catalysts (HECs), including high-entropy alloys and high-entropy oxides, have emerged as a transformative class of catalytic materials owing to their exceptional compositional flexibility and entropy-stabilized structures. Unlike conventional catalysts, HECs possess...

Which Interference Does 4-Bit Weight Quantization Harm? It Depends on the Operating Point

Language models are commonly served with 4-bit weights, and the format is chosen on perplexity and benchmark averages, which do not vary how strongly the context competes with the answer. A quantized model that fails to resolve such interference can answer fluently with the compe...

SrZrO3 Polyhedra with Lattice Variations Showing Efficient Piezocatalytic Hydrogen Evolution

Abstract SrZrO3 cubes with two different sizes as well as octahedra and rhombic dodecahedra have been solvothermally synthesized. Synchrotron X-ray diffraction (XRD) analysis indicates the possession of an orthorhombic crystal structure, with cubes and octahedra having greater ce...

Research trends in clean water and sanitation for sustainability a bibliometric analysis of web of science and Scopus

Clean water, sanitation, and sustainability have emerged as major interdisciplinary research themes in response to increasing concerns regarding water security, environmental degradation, public health, and sustainable resource management. This study presents a comparative biblio...

Selective sparsity–enhanced synchronization in disordered semiconductor laser networks

Biological networks tend to leverage selective sparsity as an economic strategy to optimize function while minimizing wiring costs. In contrast, achieving synchronization in engineered systems such as semiconductor laser arrays is traditionally expected to require resource-intens...

Reduced-Precision Deployment Can Keep the First Mask and Still Change How Interactive Segmenters Correct

Edge deployments of promptable segmenters are checked by the quality of the first mask or by simulated click counts, yet an interactive tool is used through its corrections. We measure deployment on the correction itself: from the same image, click history and starting mask, we c...

Decision continuity under speech compression in voice-pathology detection: A paired audit at matched false-alarm budgets

Background and objective: Telemedicine assesses voice from recordings sent over telephone and video links, where lossy speech codecs commonly sit between the voice and the screening model, and clinicians act on each patient’s flag. Codec studies report aggregate accuracy, yet two...

Accuracy-Matched Is Not Cost-Matched: Pricing and Repairing Token Inflation in INT4 Reasoning Models

INT4 weight quantization is accepted for a reasoning model when it preserves accuracy, but a reasoning model chooses how many tokens it generates, so an INT4 model that matches BF16 accuracy can still cost more per solved problem. Here we price a compressed reasoner by its genera...

Which Interference Does 4-Bit Weight Quantization Harm? It Depends on the Operating Point

Language models are commonly served with 4-bit weights, and the format is chosen on perplexity and benchmark averages, which do not vary how strongly the context competes with the answer. A quantized model that fails to resolve such interference can answer fluently with the compe...

Removing the Competitor Is Not Enough: Reallocating Attention to the Current Value Restores Recall under Proactive Interference

When one key is updated again and again within a single context, language models answer with a value that has already been overwritten, long before the context window fills. Suppressing attention to the stale value reduces those answers, but no study has held the deletion fixed a...

Removing the Competitor Is Not Enough: Reallocating Attention to the Current Value Restores Recall under Proactive Interference

When one key is updated again and again within a single context, language models answer with a value that has already been overwritten, long before the context window fills. Suppressing attention to the stale value reduces those answers, but no study has held the deletion fixed a...

Economies of Scale to Consumption in Collective Households

ABSTRACT Browning et al. (2013) model collective‐household economies of scale in goods consumption by having each good be partly shared, instead of each good being public or private. We modify their model to achieve simple point identification and estimation of the economies of s...

Anytime-Valid Stopping for Self-Consistency on Open Answer Sets

Self-consistency samples reasoning chains and returns the most frequent answer, and adaptive variants stop sampling early to save compute. Deployments act on the stopped answer, yet these rules check a posterior or window criterion as draws arrive, so the chance of stopping on an...

Covariate Copies Count as Evidence in Time-Series Foundation Models

Covariate-aware time-series foundation models forecast a target from the related series supplied with it, and which series they receive depends on how a pipeline was built: the same sensor exported twice, a temperature in two units, one weather station joined in for several zones...