National Science Centre

Epitope and immunological basis for superior immunogenicity of henipavirus glycoprotein HeV.G over NiV.G in mRNA vaccines

Nipah (NiV) and Hendra (HeV) viruses are highly lethal zoonotic Henipaviruses with pandemic potential, for which no licensed vaccines exist. The surface glycoprotein (G) is the primary target of neutralizing antibodies, yet a systematic comparison of the immunogenicity of NiV.G a...

Naoluotong granules inhibit necroptosis of neural cells and improve cerebral ischemia-reperfusion injury by regulating the RIP1/NIK/IKKα/NF-κB pathway.

BACKGROUND: Cerebral ischemia-reperfusion can cause structural changes in brain tissue and disrupt physiological functions. Naoluotong granules (NLT) exhibit significant neuroprotective effects on brain nerve cells and are widely utilized in treating cerebral ischemia-reperfusion...