National Research Mordovia State University

Clinical heterogeneity and neurobiological mechanisms of asthenia

Asthenia is a multifactorial disorder characterized by increased fatigue, reduced functional capacity, and cognitive disorders. Its high prevalence and clinical heterogeneity underscore the need for improved diagnostic and patient management strategies, especially in primary care...

The relationship between colorectal cancer and atherosclerosis-related cardiovascular diseases

Objective of the review. To evaluate the associations between colorectal cancer and atherosclerosis-related cardiovascular diseases, and to identify common risk factors. Materials and methods. Data for this analysis were collected from peer-reviewed articles published between 200...

Cardiovascular and functional outcomes of glucagon-like peptide−1 receptor agonists in heart failure with preserved or mildly reduced ejection fraction: a systematic review and meta-analysis of randomized controlled trials

Heart failure with preserved (HFpEF) or mildly reduced ejection fraction (HFmrEF) accounts for more than half of heart failure (HF) cases and is strongly associated with obesity and metabolic dysfunction. Glucagon-like peptide−1 receptor agonists (GLP-1RA) provide cardiometabolic...

Efficacy and Safety of Baxdrostat for Patients With Uncontrolled or Resistant Hypertension: A Systematic Review and Meta-Analysis

We evaluated the efficacy and safety of baxdrostat in adults with uncontrolled or resistant hypertension. We searched PubMed, Scopus, Web of Science, and Cochrane CENTRAL from inception to January 2026. We included randomized controlled trials that involved hypertension patients...