National Research Council

A Synergistic Experimental and Computational Approach to the Design of MIPs Targeting Metronidazole

Abstract Metronidazole (MTZ) is a widely used nitroimidazole antibiotic, and its persistence has raised growing concerns as an emerging environmental contaminant. This study focuses on the design of an electrochemical sensor based on Molecularly Imprinted Polymers (MIPs) for its...

Emerging therapeutic strategies and clinical trials in severe asthma management: current evidence and future directions

Introduction Biologic therapies have transformed the management of severe asthma, particularly in type 2-high disease, but important unmet needs remain. Incomplete responses, uncertainty in treatment positioning, and the lack of effective options for non-type 2 or mixed inflammat...

Interfacial Electric Fields in Water Nanodroplets Are Weakly Dependent on Curvature and pH

Abstract The origin of enhanced reactivity in aqueous microdroplets remains unresolved, with interfacial electric fields (IEFs) frequently proposed as catalytic drivers. Here, we present a quantum-mechanical, spatially resolved characterization of the electric field at air-water...

Cellulose-Based Nanosponges with PEDOT:PSS as Pressure Sensors with Tunable Elasticity: A Study on Modulation of Mechanical Properties and Pressure Response

Abstract This study investigates the suitability of sustainable, highly porous nanosponges, composed of TEMPO-oxidized cellulose nanofibers (TOCNF) and branched polyethylenimine (bPEI, cross-linker), as scaffolds for PEDOT:PSS poly(3,4-ethylenedioxythiophene):polystyrenesulfonate...

Vitamin D in coronary heart disease: a Mendelian randomization meta-analysis of data stratified by 25(OH)D levels

Maria Fusaro, Pasquale Perrone Filardi, Gianfranco Sinagra, Maria Luisa Brandi, Maurizio Gallieni, Jean-Yves Reginster, Eugene McCloskey, Etienne Cavalier,

The functional impact of myofiber macroscopic organization and disarray in computational models of the murine heart

A major challenge in computational models of cardiac electromechanics is the reconstruction of myocardial fiber architecture, as direct in vivo measurements of fiber orientation are not feasible. Consequently, rule-based methods are commonly adopted as surrogates, relying on empi...

Urban Green Walls under Traffic Stress: Linking the Elemental Composition of Particulate Matter Deposition to Plant Physiological and Gene Expression Responses

Abstract This one-year study integrates multi-elemental fractionation, physiological, and gene expression analyses to investigate PM retention and plant responses in a nine-species green wall at a high-traffic urban site. A chemical fractionation approach was optimized to discrim...

A Novel Analytical Strategy to Detect Specific Markers of Nitrofurazone from Protein-Bound Metabolites in Food Animals

Abstract Accurate detection of nitrofuran residues, as an indicator of banned drug use, in animal-derived food products is vital for ensuring food safety. The accepted regulatory approach for nitrofurans produces a residue marker from their protein-bound metabolites, which is non...

Transformative hospitality through community-led artistic interventions

Purpose This study aims to examine how community-led artistic interventions activate early-stage processes of transformative hospitality. It is based on the case of Altofest, an international contemporary art festival in Naples. Design/methodology/approach This qualitative interp...

Positive ion mass spectrometry enables simplified radiocarbon analysis

Abstract Radiocarbon ( 14 C) analysis underpins research and regulation across archaeology, Earth system science, the life sciences, and bio-content verification, yet remains constrained by reliance on accelerator mass spectrometry (AMS). Although AMS delivers the sensitivity req...

Thermal Hydrolysis-Driven Lactate Enrichment and Caproate Specificity in Self-Buffered Mixed Waste Fermentation: Mechanistic Insights into a Long-Term Integrated Chain Elongation and Anaerobic Digestion Process

Abstract This study demonstrates a sustainable continuous production of medium-chain fatty acids (MCFAs) from real waste streams, achieving stable caproate synthesis without external buffering or electron donor addition. This new process couples microbial chain elongation of mixe...

Movement of European freshwater mussels under simulated dewatering conditions

Freshwater ecosystems are exposed to altered hydrological regimes due to climate change and poor water management, resulting in frequent and intense dewatering events. Freshwater mussels (Unionida) are particularly vulnerable to rapid water-level declines. Dewatering can lead to...

MSP4BIO Deliverable 3.4: Ecological toolkit (ESE1) for MPAs prioritization and networking

The Ecological Toolkit (ESE1) was developed to support the design, establishment and management of Marine Protected Areas (MPAs) by improving decision-making processes, focusing on prioritisation of areas, integration of connectivity processes and assessment of human impacts on m...

MSP4BIO Deliverable 3.4: Ecological toolkit (ESE1) for MPAs prioritization and networking

The Ecological Toolkit (ESE1) was developed to support the design, establishment and management of Marine Protected Areas (MPAs) by improving decision-making processes, focusing on prioritisation of areas, integration of connectivity processes and assessment of human impacts on m...

Psychometric properties of the adult executive functioning inventory (ADEXI) in adults with attention-deficit/hyperactivity disorder (ADHD)

The Adult Executive Functioning Inventory (ADEXI) is a brief novel self-report questionnaire designed to assess executive functioning. The aim of this study was to evaluate the psychometric properties of its Italian version in adults with attention-deficit/hyperactivity disorder...

Does an Unconventional Source with a High Silica Content (Obsidian) or a High Alumina Content (Bauxite) Affect the Type of Potassium Zeolite Formation? Preliminary Data on Synthetic Products’ Efficiency in Ammonium Removal

In this paper, obsidian (OS) and bauxite (BX) are used to synthesize zeolites via KOH prefusion, followed by a conventional hydrothermal process (HY) or an unconventional vapor-phase crystallization method (VPC) at 90 °C. The results indicate that, due to their chemical and miner...

Helicopter Ditching According to the European Union Aviation Safety Agency CS-29

This paper outlines the methodology and results of scale-model tests of a helicopter ditching maneuver. The experimental campaign aims to support the study and certification of helicopters for maritime operations, in accordance with the requirements set by the European Union Avia...