National Public Health Laboratory

An Integrated Mobile Laboratory Workflow for Wastewater and Environmental Pathogen Surveillance: Performance Evaluation and Field Application in Sub-Saharan Africa

Abstract Mobile laboratories (MLs) offer a practical solution for decentralized wastewater and environmental surveillance in settings with limited laboratory infrastructure, cold-chain logistics, and trained personnel. However, field-deployable molecular workflows suitable for di...

Strengthening systems to monitor antibiotics. An action oriented approach

Background Antibiotics have become lynchpins of our modern systems of healthcare, animal health and agriculture. Monitoring the types and volumes of antibiotics distributed, used and discharged across these systems is critical to provide evidence for action. With limited resource...

Analytical performance verification of the Deeplex Myc-TB assay using well-characterized Mycobacterium tuberculosis proficiency testing isolates

Rapid and accurate detection of drug-resistant Mycobacterium tuberculosis is critical for effective patient management and tuberculosis (TB) control. Targeted next-generation sequencing (tNGS) assays such as Deeplex® Myc-TB offer rapid detection of resistance-associated mutations...

Prevalence of high-risk human papillomavirus genotypes and associated factors among HIV-infected women in a reproductive age group attending antiretroviral therapy in Nekemte town, Oromia, Ethiopia

Background Human papillomavirus is a deoxyribonucleic acid virus transmitted primarily sexually. Infection with high-risk human papillomavirus is recognized as the key cause of cervical cancer that is leftover as a public health problem globally. Human immunodeficiency virus infe...

Knowledge, attitude, and practice of antifungal resistance and stewardship among pharmacy students in Zambia: a cross-sectional study to inform antifungal stewardship programs

Background Antifungal resistance (AFR) is a growing global health threat, particularly in low- and middle-income countries such as Zambia, where antifungals are often accessed without prescription. Antifungal stewardship (AFS) programs aim to optimise antifungal use, yet limited...