National Nutrition and Food Technology Research Institute

Berberine as a Mitochondrial Metabolic Reprogrammer in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): Adaptive Energetic Stress, Quality Control, and Translational Limitations

Metabolic dysfunction-associated steatotic liver disease (MASLD) is closely linked to mitochondrial dysfunction, including altered oxidative phosphorylation, disrupted fatty-acid oxidation, redox imbalance, abnormal mitochondrial dynamics, and impaired quality control. Berberine...

Dietary amino acid patterns and epilepsy among the PERSIAN cohort population: A cross‐sectional study

Abstract Epilepsy is characterized by the occurrence of at least two unprovoked seizures occurring more than 24 h apart, reflecting a predisposition to recurrent epileptic events. The role of dietary amino acids (AAs) in epilepsy is not clearly understood. To the best of our know...

Association between dietary fatty acids and all‐cause mortality in patients with cirrhosis: A cohort study

Abstract Liver cirrhosis imposes a substantial global burden, with complications driving high mortality. Diet is pivotal in managing liver disease progression and cirrhosis‐related death. This study investigated associations between total fat intake, specific dietary fatty acid s...

Ultra-processed food consumption (NOVA index) and the odds of diabetic nephropathy in women: a case-control study

diabetic nephropathy (DN) is a major complication of diabetes mellitus associated with increased morbidity and mortality. Dietary factors, particularly unhealthy food consumption, may contribute to kidney dysfunction. This study aimed to investigate the association between the NO...

Association between dietary phytochemical index and pancreatic steatosis in patients with common bile duct stones

The dietary phytochemical index (DPI) may protect against pancreatic steatosis (PS), but evidence is limited. This study examined the association between DPI and PS risk. This case-control study included 278 patients with common bile duct stones at Taleghani Hospital, Tehran, bet...

Association of dietary phytochemical index (DPI) with psychological disorders and serum levels of adropin and brain-derived neurotrophic factor in Iranian adults

Considering the contradictory findings of earlier studies in terms of association between dietary phytochemical index (DPI) and psychological disorders, this study evaluated relationship between DPI and psychological disorders (as primary outcome), regarding their association wit...

Intermittent fasting in diabetic retinopathy: microbiome modulation, mechanisms, and clinical insights.

Intermittent fasting, a nonpharmacological approach, shows promise for controlling diabetic retinopathy but lacks concrete human evidence directly associating intermittent fasting with eye responses. This review highlights preclinical research insights about intermittent fasting...

The effect of reduced carbohydrate diet on cardiometabolic risk factors and gut microbiota in children and adolescents with obesity: a randomized controlled trial

Abstract Objective To compare the effects of a reduced-carbohydrate diet (RCD) with a standard diet (STD) on cardiometabolic risk factors and gut microbiota composition in children and adolescents with obesity. Methods In this randomized controlled trial, 84 children and adolesce...