National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I.Kulakov of the Ministry of Healthcare of the Russian Federation

Disentangling the Effects of Craniotomy and Traumatic Brain Injury in Experimental Models: A Narrative Review

Many widely used open-head models of traumatic brain injury (TBI) require craniotomy before injury, while sham-operated animals undergo surgery without impact and serve as controls. However, sham surgery itself may alter physiological, molecular, and behavioral parameters, compli...

Anesthetic management for patients with morbid obesity undergoing robot-assisted gynecological surgery: pathophysiology, risks, and contemporary approaches (a narrative review)

The prevalence of morbid obesity (BMI ≥40 kg/m²) among women of reproductive age is increasing, leading to a growing need for surgical treatment of gynecologic pathology. Robot-assisted procedures expand the possibilities of minimally invasive surgery but create specific anesthet...

Amino Acid Profiles in Dried Blood Spots and Clinical Outcomes in Selective Fetal Growth Restriction: A Twin-Pair Study

Selective fetal growth restriction (sFGR) remains a leading cause of perinatal morbidity in multiple pregnancies; however, its pathogenesis is not yet fully elucidated. Investigating amino acid metabolism in weight-discordant twins may uncover critical metabolic pathways involved...

Macrophage Density Patterns in Uterine Leiomyomas Across Patient Age Groups: Evaluation of Separately Quantified CD68-Positive and CD163-Positive Cells

Tumor-associated macrophages (TAMs), key effectors of the innate immune system, actively participate in extracellular matrix remodeling, angiogenesis, and tumor growth. However, their age-associated quantitative and phenotypic distribution in uterine leiomyoma microenvironment re...

RGB LED-induced fast photochemical synthesis and photothermal effect of silver nanoprisms

A critical challenge in nanomaterials science is the development of high-throughput, reproducible, and economically viable syntheses capable of yielding nanoparticles with well-defined characteristics. Addressing the poor reproducibility of conventional methods is essential for t...

Results of the meeting of the Interdisciplinary Expert Council on an integrated approach to the management of peri- and postmenopausal women with psycho-emotional and neurological disorders

The reduction in sex hormone levels during the menopausal period substantially impacts patients' quality of life and serves as a significant risk factor for psycho-emotional disorders. Current clinical guidelines from both Russian and international sources recognize menopausal ho...

Results of the meeting of the Interdisciplinary Expert Council on an integrated approach to the management of peri- and postmenopausal women with psycho-emotional and neurological disorders

The reduction in sex hormone levels during the menopausal period substantially impacts patients’ quality of life and serves as a significant risk factor for psycho-emotional disorders. Current clinical guidelines from both Russian and international sources recognize menopausal ho...