National Library of Scotland

The Association Between Chronic High-Altitude Exposure and Increased Pulmonary Vascular Resistance in Healthy High-Altitude Residents: A Systematic Review and Meta-Analysis

00:00-00, 2026. BACKGROUND: At high altitude, hypoxia triggers pulmonary vasoconstriction and vascular remodeling, potentially elevating pulmonary vascular resistance (PVR). Whether chronic high-altitude exposure raises PVR to clinically meaningful levels remain unclear, particul...