National Institute of Pharmaceutical Education and Research

Safety and efficacy of indigenous ultrathin-strut versus international thin-strut drug-eluting coronary stents in percutaneous coronary intervention: a systematic review of randomized controlled trials

Introduction Ultrathin-strut drug-eluting stents (DES) have been developed to enhance vascular healing and reduce restenosis following percutaneous coronary intervention (PCI). Indigenous biodegradable-polymer ultrathin-strut DES are increasingly used in high-burden settings; how...

White analytical chemistry-driven, blue-guided LC-MS/MS method for simultaneous quantification of metformin and sitagliptin in human plasma

Abstract A liquid chromatography-tandem mass spectrometry method was developed for the simultaneous determination of metformin (MET) and sitagliptin (SIT) in human plasma. Chromatographic separation was achieved on an Endurus C18 pro-XR 4.6 × 100 mm column, using methanol and 2 m...