National Institute of Genetic Engineering and Biotechnology

Localized brain delivery of drugs via focused ultrasound-responsive bi-layer nanobubbles

Focused ultrasound (FUS) in combination with micro- or nanobubbles is a promising strategy for transiently and non-invasively opening the blood-brain barrier (BBB) to enable targeted drug delivery to the brain. Here, we report a FUS-responsive delivery system using bi-layer nanob...

Tissue-specific transcriptome analysis uncovers phenylpropanoid biosynthetic genes in Althaea officinalis

Althaea officinalis is a medicinal plant, rich in mucilage and polyphenols and traditionally used to relieve inflammation and irritation of respiratory, digestive, and urinary tissues. This study presents the first comprehensive transcriptomic analysis of A. officinalis revealing...