National Institute of General Medical Sciences

Corticosteroids drive oral candidiasis by impairing type-17 immunity without inducing interferon-gammopathy

ABSTRACT Oral candidiasis arises from either genetic immune defects or iatrogenic immune suppression, most commonly due to corticosteroid therapy. Although the cortisone acetate mouse model is widely used to study corticosteroid-associated oral candidiasis, the underlying mechani...