National Institute for Communicable Disease Control and Prevention

Detection and Distribution of Tick-Borne Bacterial Pathogens in Ticks from Different Hosts in the Altun Mountains, China

Background: Ticks are the main vectors for a variety of tick-borne bacterial pathogens. Systematic studies on the coinfection patterns and differences of pathogens in ticks derived from different hosts are of great significance. Therefore, the present study investigated ticks col...

Global Trends in Antimicrobial Resistance-Related Mortality from Klebsiella pneumoniae-Associated Lower Respiratory Infections: A GBD 2021 Analysis, 1990–2021

Klebsiella pneumoniae (K. pneumoniae) is a leading cause of hospital- and community-acquired lower respiratory infections (LRI). The emergence of antimicrobial resistance (AMR), especially carbapenem-resistant strains (CRKP), poses a serious global health threat. Using Global Bur...

An orthogonal transcription system enables high-efficiency rescue of measles virus-based vaccine vectors against multiple pathogens

Recombinant measles virus (rMeV) vectors are promising platforms for vaccine development against emerging infectious diseases due to their safety, stability, and potent immunogenicity. However, conventional rMeV rescue systems frequently exhibit low efficiency, thereby constraini...