National Development Institute of Korean Medicine

Ent-7β-hydroxy-15-oxokaur-16-en-18-yl acetate suppresses RANKL-induced and LPS-enhanced osteoclastogenesis through NF-κB/MAPK signaling with involvement of the ACE–AT1R axis

Osteoporosis is a metabolic bone disorder characterized by excessive osteoclast-mediated bone resorption, which is exacerbated by inflammatory and oxidative stress-associated signaling pathways. Although anti-resorptive drugs are used to prevent excessive bone resorption, their l...