National Chung Hsing University

Sfp1 Contributes to Fluconazole Responses and Virulence in Candida albicans

Candida albicans is an important human fungal pathogen. Previous studies have shown that the transcription factor Sfp1 is involved in regulation of various biological processes in C. albicans, including cell wall maintenance, biofilm formation, oxidative stress responses, and car...

Bioinformatics-Driven Identification of Flooding-Tolerance Genes and Their Structural and Molecular Characterization in Soybean

Abstract Flooding stress is one of the important abiotic factors restricting soybean production globally. Despite numerous efforts, the genetic mechanisms of flooding tolerance are not fully understood. This work used a bioinformatics-driven, integrative approach combining struct...

Probabilistic tsunami risk assessment based on submarine active faults and their possible interactions in the sea of Japan

Abstract The Sea of Japan coastal areas have experienced tsunami damage caused by submarine active seismic faults. Large uncertainties remain regarding seismic activity of these faults and the following tsunami. Probabilistic tsunami risk assessment (PTRA) enables the evaluation...

A broad-host-range Rhizobium rhizogenes strain enables transient expression across diverse crop species

Agrobacterium -mediated transient expression has revolutionised plant research, enabling numerous landmark discoveries across diverse areas of plant biology. Yet this powerful approach remains largely confined to solanaceous species, leaving most economically important crop famil...

Influence of Precipitation Sources on Pareto-Optimal Parameter Sets and Hydrological Partitioning in SWAT+

Accurate precipitation inputs are essential for watershed hydrological modeling, yet different precipitation datasets may produce similar streamflow performance through different calibrated parameter combinations and hydrological process representations. This study evaluated the...

Pseudobulb Yield and Chemical Quality of Field-Grown Bletilla formosana in Guangfu, Hualien, Across Cultivation Years and Harvest Seasons

Bletilla formosana is an important medicinal orchid in Taiwan, but information on how cultivation year, harvest season, and pseudobulb size are associated with yield and chemical quality under field conditions remains limited. This study evaluated field-grown B. formosana in Guan...

Artificial Grain Boundaries Created by Freestanding Membrane Transfer Reveal Angle‐Dependent Ferroelectric Switching and Leakage in BaTiO 3

ABSTRACT Grain boundaries (GBs) strongly influence polycrystalline ferroelectrics, but their discrete effects are difficult to isolate because of nanoscale heterogeneity. Here, we use freestanding membrane transfer to fabricate artificial GBs with controlled, experimentally acces...

Comparative operative performance of three robotic platforms in benign gynecologic surgery: a single-surgeon retrospective cohort study

This single-surgeon retrospective cohort study compared operative efficiency and perioperative outcomes among the da Vinci Xi, Hugo RAS, and da Vinci SP platforms in 218 women undergoing robotic hysterectomy or myomectomy for benign disease. The primary outcome was console time;...

Modular Synthesis of C5 Sulfur‐Functionalized Oxazolidinones via Thiol‐Induced Cascade Reactions of Epoxy Carbamates

ABSTRACT A modular cascade strategy has been developed for the synthesis of C5 sulfide‐functionalized oxazolidinones from epoxy carbamates and structurally diverse thiols. The transformation is initiated by intermolecular nucleophilic epoxide ring opening and followed by intramol...

Using machine learning and preoperative data to predict 30-day mortality after non-cardiac major surgeries in older patients

Postoperative mortality remains a critical concern, especially among older patients undergoing non-cardiac major surgeries. With over 300 million surgeries performed worldwide annually, a significant proportion involves elderly patients, making early and precise risk stratificati...

Microscope-Integrated Augmented Reality-Assisted Navigation for C1–C2 Instrumentation: A Retrospective Single-Center Case Series

Objective: Posterior C1–C2 instrumentation is technically demanding because of the complex osseous and vascular anatomy of the atlantoaxial region. This retrospective single-center case series aimed to describe the technical feasibility and observed screw-placement outcomes of a...

CAN-Promoted Boc2O-Mediated Cascade Conversion of Aziridines to Oxazolidinones

Abstract An efficient CAN-promoted Boc2O-mediated cascade conversion of aziridines to oxazolidinones has been developed. The transformation proceeds under mild, CO2-free conditions and provides structurally diverse oxazolidinones in 16–99% yields (46 examples), with gram-scale re...

Clinical Implications of the Novel Genetic Polymorphism Associated With Retinal Vein Occlusion: The East Asian GWAS Survey in a Single-Center Taiwanese Cohort

Purpose: To explore the single-nucleotide polymorphic features in an East Asian cohort of retinal venous occlusion (RVO) patients, to map pathogenic genes, and to analyze potential pathophysiological associations. Methods: This was a cross-sectional monocentric cohort study invol...

Nitrogen-doped MOF-derived carbon hosts for aluminum-sulfur batteries: Polysulfide confinement and sulfur-loading limitations

Despite being a highly attractive candidate for advanced energy storage systems, aluminum‑sulfur (Al S) batteries suffer from restricted practical viability due to severe polysulfide shuttling and inherently slow redox kinetics. To tackle these issues, a ZIF-67-templated hierarch...

Superinfection Exclusion Between Japanese Encephalitis Virus Genotypes I and III Occurs During Viral Entry

Superinfection exclusion occurs when a primary viral infection prevents subsequent infection of the same cell. Japanese encephalitis virus (JEV) comprises several genotypes that differ primarily in their envelope protein sequences, and a shift in predominance from genotype III (G...

Standardized Short-Wave Infrared Hyperspectral Imaging for Non-Destructive Spectral Comparison of Coin Denominations, Design Variants, and Surface-Use Conditions

Coins contain multiple types of information, including denomination, design variant, year of issue, and surface condition. This study established a standardized 900–1700 nm short-wave infrared hyperspectral imaging (SWIR-HSI) workflow for controlled and non-destructive spectral c...

Impacts of Climatic Factors on Milking Frequency and Milk Yield in Automatic Milking Systems Under Hot-Humid Conditions

Heat stress in hot and humid environments can severely limit the expected advantages of automatic milking systems (AMSs). This study was conducted to investigate the environmental thresholds for milking frequency (MF) and milk yield (MY) in AMSs under hot and humid conditions. We...

Brine Pretreatment Improves Ion-Exchange Resin Regeneration with Associated Physicochemical Changes

Abstract Regeneration efficiency governs the long-term performance and sustainability of ion-exchange processes, yet resin fouling and limited accessibility of exchange sites can restrict regeneration effectiveness and ion transport. This study investigates controlled brine pretr...

Hydrogen Bonds Regulate Paramagnetic Spin Delocalization in Ferric Hemes

Abstract Hydrogen bonds in metalloprotein active sites regulate reactivity and facilitate electronic communication between metal centers and their surrounding environment. However, systematic control over hydrogen-bond-mediated spin delocalization has not been achieved in a synth...

Fig. 2 in Zavreliella shidai Cao & Tang, 2017, sp. n.

(De Haan, 1844), from the main islands of Japan.