National Chemical Laboratory

Engineering nickel-based catalysts for time-efficient cyclohexanol and cyclohexane production under mild conditions: role of loading, support, and oxidation state

Lignin is the largest renewable source of aromatic compounds, representing an attractive feedstock for the sustainable production of renewable fuels and sustainable aviation fuel (SAF) precursors. Hydrodeoxygenation (HDO) of lignin-derived phenolics is a key upgrading strategy; h...

Disruption of paramyosin compromises muscle integrity and alters systemic trehalose metabolism in Helicoverpa armigera

Abstract Trehalose is a principal circulating sugar in insects, maintaining a critical balance between energy supply and storage through systemic insulin signalling. Among different tissues, insect muscle functions as a metabolic hub, coordinating trehalose utilization and glucos...

Sustainable and solvent-free delamination of spent LFP cathodes and their direct regeneration via stoichiometric hydrothermal re-lithiation

As the use of electric vehicles increases, sustainable end-of-life management of lithium iron phosphate (LFP) batteries becomes more crucial. However, because of their low intrinsic metal value and chemically stable olivine framework, traditional recycling methods such as pyromet...

Complete Isocyanide Triple Bond Scission by a Silylene Yields an Optoelectronic 1,3-Disilacyclobutene

Abstract The complete scission of strong triple bonds is a definitive hallmark of transition metals, typically remaining beyond the reach of main-group elements. Despite the success of silylenes in activating various inert linkages, the full fragmentation of the isocyanide C≡N mo...

Odd-Nuclearity in Homologous Series of Ni-Tiara Clusters Unlocking Near-Unity NH3 Selectivity in Electrochemical Nitrate Reduction

Abstract Electrochemical nitrate reduction to ammonia offers a sustainable alternative to the Haber-Bosch process while mitigating nitrate pollution. However, the development of nitrate reduction reaction catalysts is hindered by ambiguous active-site structures, poorly understoo...

EnT-Mediated Imino-Sulfonylation of Methylenecyclopropanes Using Bifunctional N -Sulfonyl Imines: Access to β-Amino Sulfone Derivatives

Abstract Herein, we present a visible light-driven difunctionalization strategy for the efficient synthesis of β-amino sulfone derivatives from methylenecyclopropanes and N-sulfonyl imines under mild conditions. The process involves an energy transfer (EnT)-mediated pathway, wher...

Phage treatment reduces multidrug resistant Pseudomonas aeruginosa biofilms and sewage pseudomonads

Untreated wastewater can retain antimicrobial-resistant bacteria, yet phage performance is inferred from simplified host systems. We evaluated genome-resolved lytic phage ɸPRS-1 against Pseudomonas aeruginosa PAO1 in planktonic and single-strain biofilm assays, wastewater-derived...

Crocetin HaltsTumorigenesis in Metastatic BreastCancer via Disrupting CYP2J2/EET Axis

Abstract CYP2J2 catalyzes the conversion of arachidonic acid into epoxyeicosatrienoic acids (EET), which have gained significant attention due to their oncogenic properties. Differential overexpression of CYP2J2 in tumors results in increased EET production. The role of EET in tu...

Lighting Hidden Traces: Rapid Green Synthesis of Zero‐Dimensional Manganese Halide Perovskite for X‐Ray and Fingerprint Imaging

ABSTRACT Lead‐free, eco‐friendly organic–inorganic manganese halides (OIMnHs) have attracted considerable attention for optoelectronic applications, owing to their outstanding optical properties and facile solution processability. Here, we present a novel zero‐dimensional (0D) OI...