National Center for Emerging and Zoonotic Infectious Diseases

Outdoor attractive targeted sugar bait Phase III trials for malaria control in Kenya, Mali, and Zambia: An individual participant data meta-analysis

Attractive targeted sugar baits (ATSB) are a potential new class of vector control tool that act through an “attract and kill” mechanism on mosquitoes. We conducted a meta-analysis using data from three large-scale Phase III trials of the Westham Sarabi v1.2 ATSB (0.11% dinotefur...

Phenotypic insecticide resistance in Jamaican Aedes spp. and resistance-associated transcripts in Aedes aegypti

Insecticide resistance in mosquito vectors threatens control of vector-borne diseases across the Caribbean. In Jamaica, resistance in Aedes aegypti has been documented in both urban and rural settings, while susceptibility of other potential vector species and transcriptional res...

BTX-A51 treatment modulates host innate immune responses via NF-κB and β-catenin signaling during Rift Valley fever virus infection in vitro

Rift Valley fever virus (RVFV) is a zoonotic and mosquito-borne hemorrhagic pathogen of high pandemic potential, endemic to most countries in Africa. It most severely causes disease in small domestic ruminants and is transmitted to humans. RVFV has been declared a priority pathog...

A Multistate Investigation of Serious Adverse Events, including Deaths, following Ceftriaxone Injections, September 2024–August 2025

BACKGROUND: Reports of ceftriaxone serious adverse events (SAEs), including deaths, from multiple jurisdictions during December 2024-January 2025 prompted a nationwide investigation to evaluate product safety, characterize SAEs, and assess for changes in baseline adverse event oc...

Epidemiology of Single-Etiology Non-Shiga Toxin-Producing Escherichia coli Outbreaks Reported to the National Outbreak Reporting System, with Comparison to Shiga-Toxin Producing E. coli and Shigella, United States, 2009-2023.

(EPEC). During 2009-2015, six EPEC outbreaks occurred compared with 105 during 2016-2023. This trend underscores the substantial effect of CIDTs on our understanding of enteric disease epidemiology, the importance of continued non-STEC outbreak surveillance and the need for case-...

Extracellular membrane vesicles—previously unrecognized components of Staphylococcus aureus biofilms

ABSTRACT Staphylococcus aureus is a leading cause of biofilm-associated infections, in which communities of bacterial cells are encased in an extracellular matrix composed of polysaccharides, proteins, and extracellular DNA (eDNA) that protect bacteria from host immune defense an...

Possibilities and Limitations for Conducting Wastewater and Environmental Surveillance in Refugee Camps Worldwide.

. 2026;116(8):1229-1233. https://doi.org/10.2105/AJPH.2026.308433).