National Center for Drug Screening

A Light-ControlledDNA Nanoclaw Machine: IntegratedMultiplexed Recognition, Spatiotemporally Programmable Therapy, andReal-Time Electrochemical Signaling for Precision Receptor Regulation

Abstract Cell membrane receptors are pivotal targets in precise therapeutics, yet their ubiquitous expression across tissues remains a fundamental barrier to achieving cell-specific intervention. To overcome the limitations of conventional monotargeting approaches, we developed a...