National Center for Communicable Diseases

Pilot Evaluation of ddPCR-Based NIPT for Fetal Trisomy Screening in Advanced-Maternal-Age Pregnancies in Mongolia

Background/Objectives: Advanced maternal age (≥35 years) significantly increases the risk of fetal chromosomal abnormalities, particularly trisomies 21, 18, and 13. Non-invasive prenatal testing (NIPT) based on cell-free fetal DNA (cffDNA) in maternal plasma has substantially imp...