National Cancer Centre Japan

A study to learn how well HER3-DXd (patritumab deruxtecan) works and how safe it is in people with previously treated non-small-cell lung cancer that has a mutation in the EGFR gene: a plain language summary of the HERTHENA-Lung01 study

Plain Language SummaryWhat is this summary about?This is a summary of the publication about the HERTHENA-Lung01 study, which was published in the Journal of Clinical Oncology in September 2023. The study included 277 adults with non-small-cell lung cancer (NSCLC) that had a mutat...

Treatment Outcomes for Gastric Cancer With Positive Peritoneal Lavage Cytology or Localized Peritoneal Metastasis

Importance In the era of modern systemic chemotherapy, the optimal treatment strategy for gastric cancer with positive peritoneal lavage cytology (CY1) and/or localized peritoneal metastasis (P1a) remains controversial. Objective To explore the optimal treatment strategy for pati...

Survival Results by the Prospectively Determined Clinical Staging for Locally Advanced Gastric Cancer: A Follow‐Up Study of JCOG1302A

ABSTRACT Background Long‐term overall survival (OS) of gastric cancer stratified by the prospectively determined clinical stage remains unclear. Methods This is an ancillary study of JCOG1302A, a prospective observational study that evaluated the accuracy of clinical diagnosis of...

Real‐World Achievement of Guideline‐Concordant Treatment and Survival in Osteosarcoma: A Nationwide Registry Study

ABSTRACT Real‐world achievement of guideline‐concordant treatment in osteosarcoma remains unclear. This study aimed to determine stage‐specific rates of guideline‐concordant treatment, evaluate their association with survival outcomes, and identify factors associated with non‐con...

Mapping implementation science in Pakistan’s health sector: a scoping review of frameworks, strategies, and implementation outcomes

This scoping review mapped how implementation science and implementation-relevant research have been used in Pakistan's health sector. Searches of PubMed, Google Scholar, PakMediNet, WHO IRIS, and major Pakistani institutional repositories identified English-language studies publ...