Nanyang Institute of Technology

Role of PANoptosis in cancer: molecular mechanisms and therapeutic insights

Abnormal cell death plays a crucial role in cancer development. Inducing tumor cell death is an important strategy for cancer treatment. Against this backdrop, with the in-depth study of the regulatory mechanisms of cell death, the discovery of interactions existing among pyropto...

Transition-metal-based catalysts for persulfate activation toward per- and polyfluoroalkyl substance degradation: mechanisms, performance, and perspectives

Per- and polyfluoroalkyl substances (PFAS) are extensively used as synthetic organic chemicals in various industrial productions that pose several harmful effects on human health and environment. In recent years, considerable research has focused on developing more efficient tech...

Efficacy and Safety of Crisugabalin for Inadequately Controlled Diabetic Peripheral Neuropathic Pain: A Randomized, Active‐Controlled, Phase 2 Trial

AIMS: Crisugabalin (HSK16149), a selective γ-aminobutyric acid (GABA) analog, has shown preliminary efficacy in controlling diabetic peripheral neuropathic pain (DPNP), but efficacy in patients with inadequate response to prior pregabalin treatment remains unknown. MATERIALS AND...

Membrane Binding Kinetics of Amphipathic Helical Peptides from Hepatitis C Virus: Quartz Crystal Microbalance with Dissipation Monitoring

Abstract Using quartz crystal microbalance with dissipation monitoring (QCM-D), we investigate the kinetics of attachment of three amphipathic helical (AH) peptides to a supported POPC lipid bilayer. The focus is on the peptides derived from hepatitis C virus (HCV) nonstructural...

Synergistic mechanism between photosynthetic performance and growth of interspecific hybrid scions in Catalpa Scop

Abstract Background and objective Grafting is a pivotal technique for clonal propagation in Catalpa , yet the regulatory mechanism by which scion genetic background coordinates photosynthetic productivity and growth remains elusive. Methods Using two-year-old Catalpa ovata seedli...

Fermentation-Derived Active Lixiviants from Heterogeneous Fruit Waste for Sustainable Hydrometallurgical Recycling of Lithium-Ion Batteries

Abstract Lithium-ion battery (LIB) recycling plays a key role in reducing global e-waste production, and hydrometallurgy is the current technology of choice due to its efficiency and reliability. Most hydrometallurgy processes use inorganic acids that are corrosive in nature, and...

Coupling Porous Architecture and Fe–F Coordination Engineering Enables Highly Reversible FeF3 Cathode Materials

Abstract Iron trifluoride (FeF3) is a promising conversion-type cathode material for next-generation lithium-ion batteries (LIBs) owing to its high theoretical capacity enabled by multielectron redox chemistry. However, its practical application is limited by sluggish reaction ki...

Liquid–Metal-Induced Metal–Support Interactions for CO2 Hydrogenation

Abstract Metal–support interaction (MSI) is central to numerous industrial heterogeneous catalytic processes yet its classical realization typically requires high-temperature treatment (typically >500 °C), which often induces metal sintering and excessive encapsulation. Herein, w...

General decay of a viscoelastic wave equation with frictional damping and logarithmic nonlinearity

This article is concerned with the energy decay of a viscoelastic wave equation with nonlinear damping and logarithmic nonlinearity, where the memory term involves a matrix-valued coefficient. We successfully establish polynomial decay rates for the solutions to this initial-valu...

A dual-path trust–risk model of GenAI continuance: Conversational attributes, psychological evaluations, and configurational patterns

The rapid advancement of generative artificial intelligence (GenAI) has transformed human–AI interaction by enabling more efficient, flexible, and conversational forms of user support. To better understand users' continuance intention, this study draws on the post-adoption satisf...

Screening and ARTP mutagenesis-based breeding of high-cellulase-producing strains

Abstract While lignocellulose is an abundant renewable resource, the discovery of microorganisms capable of degrading lignocellulose is important for its full utilization. In this study, 26 soil samples were collected from Jigongshan National Nature Reserve, Xinyang, China. The C...

In-Sensor Visible and Mid-Infrared Dual-Band Perception and Computing

Abstract Machine vision in complex environments requires hardware that can integrate multispectral sensing with real-time front-end information processing. Visible light (VIS) and mid-infrared (MIR) signals provide complementary scene information, yet existing photodetectors cann...

Reliable Diagnosis and Early Warning of Filamentous Bulking in Microaerobic Wastewater Treatment Systems under Small Data Constraints

Abstract Filamentous bulking can destabilize microaerobic wastewater treatment systems, creating a need for diagnostic methods that distinguish bulking severity. Using 532-day operational records and morphology-graded sludge samples, this study investigated filamentous-bulking dy...

Pure Spin Photocurrent in an Altermagnetic Photovoltaic Battery

Abstract Altermagnets, featuring momentum-dependent spin splitting without net magnetization, provide a promising platform for spintronic functionalities beyond conventional ferromagnets and antiferromagnets. Here, we propose an altermagnetic spin photovoltaic battery consisting...

Morphology-Controlled Transition between Interfacial Slip and Drag over a Pinned Surface Nanobubble under Electrowetting-Inspired Control

Abstract Surface nanobubbles are known to influence interfacial slip and near-wall hydrodynamics, yet the role of actively controlled nanobubble morphology in regulating momentum transfer at solid–liquid interfaces remains insufficiently understood. Here, nonequilibrium molecular...

Global Reanalysis Reveals Recurrent Cyanobacterial Enrichment in the Aquatic Plastisphere

Abstract The plastisphere is an emerging anthropogenic ecosystem hosting complex microbial assemblages. While heterotrophic colonizers are well studied, the role of primary producers such as cyanobacteria remains underexplored. Here, we reanalyzed 16S rRNA gene amplicon data from...

Protocols on X-ray Absorption Spectroscopy Measurement and Interpretation

Abstract Understanding the local electronic and atomic structure of materials is central to modern physics, chemistry, materials science, and nanotechnology. X-ray absorption spectroscopy (XAS) provides element-specific insight into these local environments through core-level X-r...

A hybrid memetic algorithm for an energy-aware distributed blocking hybrid flowshop scheduling problem with transportation time

Abstract This study examines the energy-aware distributed blocking hybrid flowshop scheduling problem (DBHFSP-E) considering transportation time. A mathematical programming model is formulated to simultaneously minimize makespan and total energy consumption, and its validity is v...

Neoadjuvant Anbenitamab and HB1801 in ERBB2 -Positive Breast Cancer

IMPORTANCE The combination of neoadjuvant taxanes with trastuzumab and pertuzumab remains the cornerstone treatment strategy in ERBB2 -positive breast cancer. Anbenitamab (a ERBB2 -biparatopic antibody that induces profound receptor clustering) and HB1801 (a solvent-free albumin-...

Determinants of a positive resection margin (R1 status) in esophageal squamous cell carcinoma: a retrospective analysis of 148,121 cases from China

To investigate risk factors for positive proximal and distal resection margins after surgery for esophageal squamous cell carcinoma (ESCC). Total initially enrolled esophageal squamous cell carcinoma patients were 148,121 cases. After strict case screening and quality control, a...