Nantong Tumor Hospital

Projected country-level health effects and service requirements of Helicobacter pylori screen-and-treat and targeted endoscopic screening, 2025–2050: a comparative modelling study

Helicobacter pylori eradication reduces gastric cancer incidence. We compared improvements in testing, treatment and endoscopic screening to identify their projected health gains and service requirements. We combined Global Burden of Disease 2023 estimates, population projections...

Mefatinib versus gefitinib as a first-line treatment for EGFR-mutated non-small cell lung cancer: a randomized, double-blind, multicenter phase III study

Mefatinib, a novel second-generation epidermal growth factor (EGFR) tyrosine kinase inhibitor that has shown promising antitumor activity in targeting non-small cell lung cancer (NSCLC) with common and uncommon EGFR- activating mutations. In this phase III, randomized, double-bli...

Clinical utility of molecular residual disease detection in early-stage resected EGFR-mutated non-small cell lung cancer

Molecular residual disease (MRD), detected through circulating tumor DNA, has emerged as a promising biomarker for surveillance in patients with early-stage non-small cell lung cancer (NSCLC) following curative-intent resection. Here we report the MRD analysis from the phase 3 EV...