Nanjing Traditional Chinese Medicine Hospital

Remote electroacupuncture conditioning protects the heart via fine-tuning the dual role of the SDF-1α/CXCR4 axis in myocardial ischemia–reperfusion injury

BACKGROUND: Remote electroacupuncture (EA) conditioning on forearm protects against myocardial ischemia-reperfusion injury (MIRI). However, the cardioprotective mechanisms of RIC have not been fully elucidated. This study aimed to investigate whether EA could balance the pro-surv...

From multifaceted mechanisms to targeted strategies: advances in PANoptosomes as regulatory hubs of PANoptosis in cancer

Programmed cell death (PCD) is a fundamental barrier to tumorigenesis, but cancer cells often evolve ways to evade single-mode death pathways. PANoptosis is a newly recognized form of PCD that integrates features of pyroptosis, apoptosis, and necroptosis. PANoptosomes organize th...