Nanchang Center for Disease Control and Prevention

Emerging frontiers in targeted and immunotherapeutic strategies for marginal zone lymphoma

Marginal zone lymphoma (MZL) comprises a heterogeneous group of indolent B-cell non-Hodgkin lymphomas. Most patients have favorable outcomes, but approximately 20% develop early relapse or progression within 24 months. Advances in molecular profiling have identified recurrent alt...

Resveratrol Maintains Hippocampal Mitochondrial Function and Inhibits Neuronal Ferroptosis to Improve Diabetes-Associated Cognitive Dysfunction via Sirt1/Shh Signaling

Background Resveratrol has been shown to play a neuroprotective role in diabetic cognitive dysfunction. We determined whether resveratrol improved diabetic cognitive dysfunction through ferroptosis regulation, and explored the potential mechanism. Methods Rats were fed with a hig...

A Dual-Key Lock Strategy for Bright Fluorescent Proteins Fabrication via Synergistic Noncovalent Activation of Aggregation-Induced Emission Luminogen

Abstract The development of simple, bio-friendly strategies to engineer bright fluorescent proteins (FPs) is crucial for biosensing and bioimaging. Conventional synthesis of FPs requires time-consuming chromophore maturation and tedious preparation, while covalent conjugation met...