Nagasaki University

The filtration performance of fabrics against particles of viral size: a systematic review

Wearing a mask is part of the comprehensive strategy to suppress transmission of the SARS-CoV-2 virus and respiratory tract infections. Despite available COVID-19 vaccines, wearing a mask has remained one of the simplest and most effective ways. There was, however, little data av...

P1.180. Retrospective RCT Study: Esophageal Cancer Surgical Reconstruction When the Gastric Tube Cannot Be Used - Jejunum vs. Colon

Abstract Topic Esophageal Cancer: Surgical Treatment of Esophageal Cancer Background Gastric tube reconstruction is the first choice for reconstructive organs in esophageal cancer surgery. However, when the gastric tube cannot be used due to some reasons, jejunum or colon reconst...

Latent space structure of retinal age: an artificial intelligence–based analysis of aging in fundus images

Abstract This study investigated whether age-related variation is organized as a geometric structure in latent space and how fine-tuning reshapes this representation. Fundus photographs from fellow eyes of patients who underwent macular surgery were retrospectively analyzed. Afte...

Identification of the Down Syndrome Critical Region 3 Gene as a Mammalian Cell Size Regulator

Using a genetic screening approach based on an inducible gene-activating system and cell sorting, Down syndrome critical region 3 (DSCR3) was isolated as a gene whose overexpression increased cell size. Fibroblasts derived from individuals with Down syndrome (DS) exhibit elevated...

Altered kinematics and muscle activities during half squats in people with ankle sprain history

Abstract Regardless of the high recurrence rate, copers manage the damage after a sprain. Copers do not experience ankle instability and continue their daily activities. However, it is unclear whether copers can use movement strategies similar to people without an ankle sprain. I...

Effectiveness of Clazosentan Combined with Ozagrel for Aneurysmal Subarachnoid Hemorrhage: A Retrospective Comparative Study

Abstract Clazosentan, a selective endothelin A receptor antagonist, has recently emerged as an essential therapy for aneurysmal subarachnoid hemorrhage (aSAH) in Japan. However, evidence regarding combination therapy with adjunctive agents remains unclear. We retrospectively comp...

Relationship between initial dose, dose intensity, and survival in unresectable pancreatic cancer treated with nanoliposomal irinotecan, fluorouracil, and folinic acid

Abstract While nanoliposomal irinotecan with fluorouracil and folinic acid (NFF) is a standard second-line regimen for unresectable pancreatic cancer (uPC) after gemcitabine-based therapy, the effects of initial dosing and relative dose intensity (RDI) in routine practice are unc...

Rheumatoid arthritis-associated peptidylarginine deiminase 4 haplotype citrullinates human immunodeficiency virus-pol and confers antiviral activity

Peptidylarginine deiminase 4 (PADI4)-mediated citrullination modulates immune responses and drives autoantibody formation in rheumatoid arthritis (RA). Two common haplotypes, defined by four exonic SNPs ( PADI4_89 , 90 , 92 , and 104 ), have been described, with haplotype 2 (the...

The potential modulating role of thyroid cysts on the association between anti–thyroid peroxidase antibodies and subclinical hypothyroidism

Abstract Background In our previous study, the absence of thyroid cysts was identified as an indicator of thyroid functional strain associated with thyroid peroxidase antibody (TPO-Ab) positivity. In individuals under this continuous functional load, higher levels of thyroid-stim...

Synergistic Ag/In Co-doping-Induced Band and InterfaceEngineering in p-Type CuSe on Carbon Fabric for a FlexibleThermoelectric Generator

Abstract In the present work, a dual-doping strategy with silver (Ag) and indium (In) in copper selenide (CuSe) nanoparticles on conductive carbon fabric (CF) has been employed with a facile hydrothermal technique. This co-doping strategy outperforms single-element doping by enab...

Longitudinal Stent Malapposition After Microcatheter Removal Is Associated With Incomplete Occlusion After Pipeline Flow Diversion

BACKGROUND AND OBJECTIVES: Flow diversion is an established treatment strategy for intracranial aneurysms; however, incomplete aneurysm occlusion remains a clinically relevant challenge. Adequate stent-vessel wall apposition is considered critical for aneurysm healing, yet the im...