Mutah University

The glymphatic connectome: a hypothesis for how metabolic waste accumulation may contribute to preferential network degeneration

Background Neurodegenerative diseases exhibit selective vulnerability, with preferential involvement of highly connected brain regions. This review explores how glymphatic dysfunction and impaired extracellular waste removal may contribute to network-specific degeneration.Methods...

ACE2 at the neurovascular–glymphatic interface: integrating the ACE2/ang-(1–7)/mas axis with brain fluid homeostasis and waste clearance

Background and aim Brain fluid homeostasis relies on coordinated interactions among the glymphatic system, intramural peri-arterial drainage, meningeal lymphatics, cerebrospinal fluid circulation, and the neurovascular unit (NVU). Emerging evidence indicates that angiotensin-conv...

Attenuation of cyclophosphamide toxicity by protective effects of curcumin in albino rats model

Abstract Background Chemotherapy primarily treats cancer by using drugs to kill cancer cells. Curcumin, a natural adjuvant, shows promise in preventing side effects. Purpose This study seeks to determine curcumin’s protective effect against cyclophosphamide toxicity. Materials an...

Numerical simulation and performance optimization of InPbI3 perovskite solar cells

In this study, InPbI 3 -based perovskite solar cells were numerically analyzed using the SCAPS-1D simulation tool. The device architecture, FTO/WS 2 /InPbI 3 /CuI, was modeled and systematically optimized. The investigation focused on the influence of parameters such as the thick...

Evaluating earnings management before and after the implementation of the IFRS-XBRL taxonomy: evidence from Jordan

Purpose This paper aims to compare “earnings management (EM)” practices proxied by “accrual-based earnings management (AEM) and real earnings management (REM)” in the years before and after the implementation of IFRS electronic financial reporting – XBRL in Jordan. Design/methodo...

Complications and Safety Profile of XEN ® Gel Stent in Glaucoma: A Five-Year MAUDE Database Analysis

Purpose To analyze adverse events associated with the XEN® Gel Stent using the FDA’s Manufacturer and User Facility Device Experience (MAUDE) database.Methods The FDA MAUDE database was queried for reports from January 1, 2020, to November 8, 2024, using the product code “KYF.” R...

Beyond Governance Compliance: Risk Management Committees, Risk Disclosure, and Financial Performance in a Frontier Market

This study is two-fold. First, it examines the impact of risk management committee characteristics on the level of risk information disclosure (financial, non-financial, and total risk disclosure). Second, it investigates the effect of risk disclosure on financial performance mea...

Generative ArtificialIntelligence in Medicinal ChemistryEducation: Student Engagement, Confidence Calibration, and Safety-RelatedUncertainty in Case-Based Learning

Abstract The current study focuses on the function and use of generative artificial intelligence in teaching medicinal chemistry, with particular emphasis on learning process dynamics, decision-making power, and confidence estimation. A total of 101 undergraduate students in phar...

Evaluation of relative safety and therapeutic efficacy of antihyperlipidemic drug regimens used alone or in combination in cardiovascular disease: randomized controlled study

Abstract Background Statin monotherapy is a cornerstone of lipid-lowering therapy for reducing low-density lipoprotein cholesterol (LDL-C) and cardiovascular risk in patients with dyslipidemia. However, many patients at moderate-to-high cardiovascular risk fail to achieve recomme...

The impact of digital supply chain integration on sustainable export performance: the role of sustainable supply chain resilience and supply chain transparency

Purpose Sustainability and resilience have become critical requirements for maintaining competitiveness in international markets. Yet export-oriented firms still struggle to meet these requirements effectively. While digitally enabled supply chains can potentially help firms in t...