Murdoch University

Estimating wastewater dilution using chemical markers and incomplete flow measurements: Application to normalisation of SARS-CoV-2 measurements

Combined sewers, which collect both wastewater and surface water, are found across the globe, especially in older urban centres. These systems pose a challenge when taking chemical and biological measurements, be that chemical contaminants, illicit drugs or — in the case of waste...

Design considerations and validation strategies for droplet digital PCR assays targeting exon junctions and rare splice-variant transcripts

Droplet digital PCR is widely recognised for its sensitivity, reproducibility and precision in quantifying target nucleic acid fragments. This technology is crucial in validating gene expression changes across various experimental settings. In particular, droplet digital PCR is h...

Artificial Intelligence-Assisted Systematic Literature Reviews in Metabolic Phenotyping: A Methodological Framework and Validation Study

Abstract Systematic literature reviews are widely acknowledged to be at the top of most evidence hierarchies but are very time-consuming and labour-intensive. The advent of artificial intelligence (AI) offers possibilities to accelerate the review process. We propose a systematic...

The chiral gyrating H’-T surface family: construction from the dual qtz – qzd nets and existence proof using a toroidal Weierstrass method

Abstract This paper provides an existence proof for a one-parameter family of chiral unbalanced triply periodic minimal surfaces of genus four. We name these gyrating H’-T surfaces because they are related to Schoen’s H’-T surfaces in a similar way as the gyroid is to the primiti...

Mapping structural heterogeneity in three-dimensional biophotonic gyroid networks using position-resolved small-angle X-ray scattering

Abstract The wings of select Papilionid and Lycaenid butterflies contain a three-dimensional gyroid network of a solid cuticle phase in air. In butterfly scales, gyroid networks are optically interesting, as they create the green colour observed in the wings of these butterflies....

An Examination into the Anti-stress and Anti-fatigue Effects of an Ashwagandha Extract (Ashwa.30™) in Stressed Adults: A Randomised, Double-Blind, Placebo-controlled Trial

Ashwagandha supplementation has been associated with reduced self-reported stress and anxiety, although most trials have used doses of 250–600 mg daily for 6–8 weeks. This study examined the effects of a low-dose ashwagandha extract (Ashwa.30™) on perceived stress, mood, fatigue,...

Phenomic Medicine and Metabolic Disease Trajectories: Measuring and Modelling the Health to Disease Continuum

Abstract Phenomic medicine is an emerging field that involves measurement and modelling of multidimensional phenotypic data to provide a systems-level framework to understand how health and disease evolve over time and inform decision making in a clinical context . Unlike genomic...

Advanced functional biochar-based hybrid nanocomposites for electrochemical sensing platforms in environmental monitoring

Biochar (BC), a stable, carbon-rich material produced by heating biomass, is increasingly used in electrochemical sensing, particularly in hybrid nanocomposite forms, because hybridization can improve electrical conductivity, catalytic activity, surface area, and interfacial char...

Management, demographic and dietary insights from 7 years of aerial shooting of feral pigs in an agricultural landscape

Context Feral pigs are one of the most destructive invasive vertebrate species in Australia. Aerial shooting is considered one of the most effective methods for causing a rapid reduction in feral pig density at a landscape scale. Aims We aimed to assess the effects of 7 years of...

The pharmacogGENEtics in Youth Depression (GENE-YD) study for personalizing antidepressant pharmacotherapy for young Western Australians – A feasibility study

Abstract Pharmacogenetic (PGx) testing to guide antidepressant prescribing is becoming increasingly available. However, its uptake into routine psychiatric practice for young people remains limited due to insufficient youth-specific evidence and uncertainty regarding optimal tria...