Mulungushi University

A systematic review of advances and challenges in stroke prevention in sickle cell disease since the STOP trials

Abstract Background Stroke is among the most disabling complications of sickle cell disease (SCD). The STOP trials established transcranial Doppler (TCD) screening with chronic transfusion as the basis of primary stroke prevention. Implementation remains uneven, however, and evid...

Investigation of the Torsion Strength of Basalt Fiber Reinforced Expanded Clay Lightweight Concrete Beam

This study explores the torsional behavior of lightweight expanded clay concrete beams reinforced with basalt fibers (BF) using finite element analysis, highlighting the importance of reinforcement type in improving torsional performance, focusing on basalt rebars, steel rebars,...

Household catastrophic out-of-pocket expenditure and the socioeconomic burden of paediatric surgery: a cross-sectional study at the highest tertiary hospital in Zambia

Globally, about 81 million people per year are driven to financial catastrophe from the costs of surgery and other related nonmedical costs, with low- and middle-income countries (LMICs) bearing the greatest burden. This study determined the catastrophic out-of-pocket (OOP) healt...

Knowledge, attitude, and practice of antifungal resistance and stewardship among pharmacy students in Zambia: a cross-sectional study to inform antifungal stewardship programs

Background Antifungal resistance (AFR) is a growing global health threat, particularly in low- and middle-income countries such as Zambia, where antifungals are often accessed without prescription. Antifungal stewardship (AFS) programs aim to optimise antifungal use, yet limited...

Factors associated with anxiety disorders among adolescents and young adults with substance use disorders at a tertiary hospital in Zambia: a retrospective chart review

Anxiety disorders are highly prevalent among individuals with substance use disorders (SUDs), yet factors associated with anxiety in this population remain poorly understood. This study aimed to identify demographic, clinical, and substance-related factors associated with anxiety...

Clinical determinants of neonatal mortality at a tertiary hospital in a resource limited setting: a retrospective cohort study

Neonatal mortality remains a significant public health challenge in low-resource settings. Understanding the independent predictors of neonatal death is essential for developing targeted interventions and improving clinical outcomes. This study aimed to identify factors associate...