Moscow State University of Fine Chemical Technologies

Programming the Aqueous Reaction State for Carnosine Manufacture: An Ex Situ PFEP Framework for Biocatalysis, Workup, Salt Conversion, and Stability

Article type: Perspective, mechanistic hypothesis, and prospective experimental framework. Aqueous peptide processing is often controlled by nominal pH even though pH records proton activity at the instant of measurement and does not specify titratable capacity, ionic composition...

Linker Engineering of Hybrid Triazole-Thiazolidine Antifungals Identifies a Promising Lead Against Drug-Resistant Candida Species

Background: The emergence of antifungal resistance and the limited number of clinically available antifungal drug classes necessitate the development of new agents with improved efficacy and safety. We investigated how linker architecture influences the antifungal activity and le...

Photo-Responsive In Situ Forming Hydrogels for Drug Delivery: A Critical Review of Polymer Matrices, Photoinitiators, and the Gap Towards Clinical Translation

Local drug delivery increasingly relies on injectable hydrogels that form directly at the x‘administration site, among which light-cured systems are of particular interest: irradiation converts a liquid precursor into a depot and can trigger drug release with high spatiotemporal...