Monash Health

P1.172. Comparison of Intraoperative Complications in Obese vs Non-Obese in Oesophageal Cancer Surgery

Abstract Topic Esophageal Cancer: Surgical Treatment of Esophageal Cancer Background Obesity is a substantial public health issue. A high body mass index (BMI) can increase surgical technical challenges, resulting in higher rates of intraoperative and postoperative complications....

P1.139. Advancing Risk Prediction After Esophagectomy: A Systematic Review of Machine Learning Models

Abstract Topic Esophageal Cancer: Other Background Esophagectomy is associated with substantial morbidity, mortality, and resource utilization. Traditional regression-based risk tools may inadequately capture complex nonlinear interactions. Contemporary evidence on machine learni...

Prediagnostic circulating 25-hydroxyvitamin D and prostate cancer-specific survival: a collaborative pooled analysis of 13 prospective studies

Abstract Background Previous research suggests higher risk of prostate cancer diagnosis in men with high vitamin D serology, but there are limited data related to prostate cancer survival. In this study, we examine the associations between prediagnostic circulating levels of 25-h...

Following the rules: which type 1 diabetes guidelines, protocols and recommendations are tertiary clinics in Australia following? A quantitative study

OBJECTIVES: This study characterises the use of type 1 diabetes (T1D) guidelines and protocols in Australian T1D clinics working with paediatric patients, and determines if management practices align with T1D-specific guidelines. METHODS: T1D clinic service leaders responded to a...

Scaling up Genomics

Introduction: Genomic testing has substantial diagnostic and clinical value in nephrology, yet integrating testing into routine care requires service-level changes to ensure timely and equitable access. Methods: We conducted an observational cohort study at four tertiary centres,...

Stroke survivors’ health priorities and targeted interventions in home-based post-discharge rehabilitation

<title>Abstract</title> Background This study aimed to describe health problems of the stroke survivors and the corresponding nursing interventions implemented during 12-week home-based post-discharge rehabilitation. Methods This was a descriptive secondary analysis within the co...

Protective role of dietary antioxidant intake on long-term effects of extreme PM2.5 exposure on respiratory health

Objective: To test whether dietary antioxidants moderated effects of PM 2.5 from coal mine fire smoke on respiratory symptoms. Methods: We conducted cross-sectional analyses of diet and respiratory symptom data from 448 members of the Hazelwood Health Study Adult cohort. Individu...

Bedside assistant models in robotic abdominal and pelvic surgery: a systematic review of operative efficiency, training exposure, and perioperative safety

Robotic surgery depends on effective bedside assistance, yet staffing models vary between physician and non-physician assistants. We systematically reviewed comparative evidence evaluating these models in robotic abdominal and pelvic surgery. A PRISMA compliant systematic review...

Latent profile analysis of postpartum depression symptoms and its associations with weight stigma and eating behaviors among postpartum women in China

Abstract Background Postpartum depression (PPD) represents a significant maternal health challenge with diverse symptom manifestations. Traditional analytical approaches that treat postpartum women as a homogeneous group may obscure distinct symptom patterns, limiting the develop...

Characterising the Beyond 50 Cohort: Preliminary Exploration of Physical and Psychosocial Health Factors and Substance Use Among a Cohort of Community Dwelling Adults Aged 50–70 Years

ABSTRACT Introduction Older adults exhibit unique risks associated with poor mental health and substance use. The Beyond 50 study is a longitudinal cohort investigating the determinants of healthy ageing, including relationships between physical and psychosocial health and substa...

Efficacy of Vitamin C Treatment to Aid the Healing of Foot Ulcers in People With Diabetes: A Randomised, Placebo‐Controlled Double‐Blind Trial: The FOOT‐C Study Protocol

ABSTRACT Introduction Diabetes‐related foot ulceration (DFU) is a serious complication, serving as a leading cause of amputation, disability, hospitalisation and a significant contributor to healthcare costs. Deficiencies in vitamin C and other micronutrients are common in DFU. E...

Issues in the clinical assessment and management of people living with motor neurone disease (MND): a survey of Australian healthcare professionals

Objective: To inform the development of the Australian MND Guideline, this study aimed to identify challenges Australian healthcare professionals (HCPs) face in the clinical assessment and management of people living with MND (plwMND) including where practice varies from evidence...

An autoinflammatory CDC42 variant M45L demonstrates the mechanism of pyrin inflammasome activation

CDC42 is an evolutionarily conserved guanosine triphosphatase (GTPase) regulating critical cellular and immune processes. Variants in CDC42 therefore cause a spectrum of developmental phenotypes, including hematological and immunological symptoms. Here, we identify a previously u...

Implementing evidence in residential aged care facilities: a longitudinal multi-method evaluation of knowledge broker evolution

Background Knowledge brokers act as intermediaries to bridge evidence-to-practice gaps. Limited evidence describes how the knowledge broker role in health settings evolves over time. This study aimed to (a) examine the evolution of knowledge broker activities over a 12-month impl...

Assessing Vancomycin‐Formyl Peptide Conjugate Binding to the Surface of Resistant Staphylococcus aureus via Flow Cytometry

Staphylococcus aureus strains have emerged with resistance mechanisms that reduce the efficacy of last resort antibiotics and evade the immune system. One strategy to combat antimicrobial resistance is to modulate host immunity to eliminate infections more effectively. This has l...

The Safety of Single Aminoglycoside Dose in Emergency Departments ( SAD ‐ ED ) Among Patients With and Without Chronic Kidney Disease: A Retrospective Cohort Study

ABSTRACT Objective Nephrotoxicity has been reported with prolonged use of aminoglycosides but is considered low‐risk with single‐dose empirical therapy. However, limited data exist in patients with chronic kidney disease (CKD). The aim of this study was to determine the safety of...