Mission Health

Sevuparin in children with severe malaria: a phase I safety and dose-finding trial

Abstract Mortality rates for African children with severe malaria remain high. Sevuparin, a heparin-like compound, as an adjunctive treatment, may improve outcomes due to its effects on Plasmodium falciparum -infected erythrocytes. A Phase I dose-finding trial in Kenyan and Zambi...

90 Developing Patient-Focused Outcomes for Routine Clinical Care in Glioma: A Synthesis of Qualitative Evidence from the COMBaT Study

Abstract Introduction There is a critical need to identify and routinely measure the outcomes that matter most to people living with glioma. Care needs in this population are complex and variable, yet current clinical practice lacks consistent, systematic approaches to assessing...