Ministry of Public Security of the People's Republic of China

Bio-inspired nanochannel sensors for detecting gaseous signaling molecules

Drawing inspiration from natural biosensing, researchers have developed artificial nanochannels that enable efficient target detection through transmembrane ionic current readout. These nanochannel sensors exhibit distinctive nanoconfined phenomena in their selectivity, gating, a...

Sequencing Deoxyuracil at Single-Base Resolution via a Hydrazine Reagent-Induced U-to-A Transition

Abstract Uracil is a canonical base in RNA, yet its presence in DNA represents the most common non-canonical modification, with broad implications for diverse physiological processes. However, due to the lack of suitable analytical methods, the distribution and biological functio...

Genetic origin and forensic analysis of han populations from four districts in Shanghai, China, based on Y-chromosome STR and SNP markers

Y-short tandem repeats (STRs) and Y-single nucleotide polymorphisms (SNPs) on the Y chromosome are genetic markers unique to men. They are widely used in identification, forensic medicine and paternal lineage tracing. Because of their strict paternal genetic characteristics, they...

Experimental and numerical investigation of ignition effects on explosion temperature fields in residential buildings

This study systematically investigates the temperature evolution characteristics of methane explosions in a full-scale residential building under various ignition scenarios through a combined approach of full-scale experiments and CFD simulations. A 280 m 3 full-scale experimenta...