Ministry of Interior

Emergency abdominal surgery: variation in closure practice and early postoperative outcomes in the prospective multicentre PROPHECY study

Emergency abdominal surgery carries a high risk of postoperative morbidity, yet prospective multicentre data on real-world abdominal wall closure practices remain limited. This interim analysis of the PROPHECY study aimed primarily to characterise current abdominal wall managemen...

Vitamins in the Management of Inferior Alveolar Nerve Sensory Disturbances: A Scoping Review of Randomized Studies

Background: Sensory disturbances of the inferior alveolar nerve (IAN) may follow dental and maxillofacial procedures and impair oral function and quality of life. This scoping review mapped randomized evidence on vitamin-based treatment of established IAN sensory disturbances. Me...

The potential use of traditional singing and dancing for respiratory health promotion in Saudi Arabia: an observational study

Singing is the production of musical tones with the voice. Like breathing, it requires breath control and uses many of the same anatomical structures. This universal human behaviour has been practiced for thousands of years in various cultural contexts, including religious ceremo...

Chemical Profiling and In Vitro Cytotoxicity Assessment of Commercial Red Yeast Rice Ingredients

Red yeast rice (RYR) food supplements are widely used for cholesterol management due to their monacolin content, particularly monacolin K (MK), which shares the same chemical structure as lovastatin, a compound associated with several side effects. The European Food Safety Author...

Efficacy and tolerability of venetoclax plus rituximab in relapsed or refractory chronic lymphocytic leukemia – real-world analysis of Polish adult leukemia study group

We collected clinical data on 363 patients with relapsed/refractory chronic lymphocytic leukemia (RR-CLL) treated with venetoclax-rituximab (VR) in a real-world setting. The median age was 69.5 years (range, 32.5–91.6 years), and the median number of prior lines of therapy was 2...

Intra-Articular Monoclonal Antibodies in Temporomandibular Joint Disorders: Current Evidence

Immune-mediated temporomandibular joint disorders involve cytokine-driven inflammation and may represent a target for biologic therapy. This paper summarizes the evidence on intra-articular monoclonal antibody administration in temporomandibular joint disorders. PubMed, Europe PM...

Clinical Meaningfulness and Improvement Thresholds of Myositis Core Set Measures: Association with Patient-Reported Outcomes

Objective The study aimed to evaluate the clinical meaningfulness and improvement thresholds of the myositis core set measures (CSMs) of disease activity in idiopathic inflammatory myopathies (IIM), emphasizing associations with patient-reported outcome measures (PROMs). Methods...