Ministry of Infrastructure and Water Management

A Comprehensive Methodology for Estimating Yearly Plastic Pollution Loads in Rivers

Abstract Plastic pollution in freshwater systems represents a major global concern, as rivers serve as critical pathways between land-based sources and marine environments. Yet, inconsistencies are observed between estimated plastic inputs from land and concentrations in the ocea...

Navigating regulatory scenarios for accelerating drug repurposing in rare diseases: a multi-stakeholder perspective on the challenges and opportunities

<title>Abstract</title> Background: The lack of treatments for patients with a rare disease calls for innovative approaches in drug development. A potential solution to accelerate therapy development is to find new therapeutic uses for existing drugs, i.e. drug repurposing. One w...