Ministry of Home Affairs

LC–MS/MS Method for Simultaneous Quantification of Zolpidem, Zopiclone, and Their Metabolites in Human Urine and Its Pharmacokinetic Application

ABSTRACT Zolpidem (Z1) and zopiclone (Z2) are widely prescribed for insomnia; but their misuse in drug‐facilitated crimes presents significant forensic and clinical challenges. This study aimed to develop and validate a simple and sensitive LC–MS/MS method, coupled with dispersiv...