Ministry of Health

Real-World Effectiveness, Documented Adverse Events, and Treatment Adherence of Semaglutide and Liraglutide in Omani Patients: A Retrospective Observational Study

Background: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are widely used in obesity and type 2 diabetes mellitus (T2DM), but comparative real-world evidence from the Middle East remains limited. We compared the effectiveness, documented adverse events, adherence and pers...

The interplay of the gut microbiome, tryptophan metabolites, and uremic toxin generation in chronic kidney disease progression

Chronic kidney disease (CKD) affects roughly 850 million people worldwide, yet the cardiovascular and immune-related mortality that classical uremic markers cannot fully explain remains the central clinical problem. Much of the small-solute uremic toxin pool is now traceable to g...

Acute kidney injury-to-chronic kidney disease transition: Maladaptive senescence, epigenetic reprogramming, and the translational frontier

Acute kidney injury (AKI) is a consistent precursor of incident and progressive chronic kidney disease (CKD). The transition reflects failed tubular repair followed by tubular atrophy, peritubular capillary rarefaction, and progressive interstitial fibrosis. Maladaptive cellular...

Cluster headache care gaps among primary healthcare physicians in the Middle East, North Africa, and Türkiye: a multinational study

Cluster headache is one of the most severely disabling primary headache disorders and is frequently associated with diagnostic delay, inappropriate treatment, disability, and substantial psychosocial burden. Because primary healthcare (PHC) physicians are commonly the first point...

Enhancing motor prosthesis training through a gamified mixed-reality system

Abstract During the advanced stages of hand prosthesis training, amputees strive to perfect their movements to enhance fine motor skills, increase speed, and achieve fluid and continuous actions. However, this training typically occurs in abstract, low-engagement scenarios, limit...

Influenza vaccine uptake, willingness, and reasons for non-vaccination among South African Hajj pilgrims in 2025

Influenza is a leading cause of morbidity at the annual Hajj pilgrimage, yet vaccination uptake among pilgrims varies across settings. This study assessed influenza vaccination uptake, willingness to accept vaccination before Hajj, and factors associated with vaccine hesitancy am...