Ministry of Health and Population

A machine learning approach to predict treatment response in myofascial pain patients receiving masseter trigger point injections

BACKGROUND: Trigger point injection (TPI) therapy is widely used for masseter myofascial pain syndrome (MPS), yet outcomes vary substantially. Individualized prediction tools are lacking, often leading to trial-and-error treatment selection. OBJECTIVE: To develop, externally vali...

Cardiac interoception as a mechanistic link between congenital mitral valve prolapse and anxiety disorders: from circuit dissection to neurotechnological modulation

Abstract Background Interoception represents the brain’s ability to sense and interpret internal bodily signals, integrating cardiovascular, autonomic, and cortical processes to maintain homeostasis and shape emotional states. Cardiac interoception links physiological signals wit...