Ministry of Health

High Expression of Aurora Kinase A (AURKA) is Associated with Aggressive Tumor Biology and Therapeutic Response in ER+/HER2− Breast Cancer

Abstract Background Aurora kinase A ( AURKA ) is a serine/threonine kinase that regulates mitotic entry, spindle assembly, and chromosomal segregation. AURKA overexpression has been linked to multiple malignancies. The biological and clinical significance of AURKA expression with...

Medical radiation at the crossroads of complexity and opportunity: New staff perceptions

Background New hospital staff represent a critical yet underexplored group in radiation safety research. Their initial perceptions and early experiences with safety systems are formative, shaping long-term professional behaviours and highlighting systemic gaps in onboarding and s...

Potentially inappropriate medication use and selected drug-related problems among older adults in Aseer Region, Saudi Arabia: a retrospective multicenter study

Older adults are at increased risk of medication-related safety concerns due to multimorbidity and polypharmacy. Potentially inappropriate medications (PIMs) and drug-related problems (DRPs) are important contributors to medication safety concerns in this population, yet hospital...

Unseen barriers to home healthcare: a qualitative study of providers’ perspectives from Saudi Arabia

This study investigated the challenges of providing care in Home Health Care (HHC) settings in Saudi Arabia. We employed a qualitative design and used thematic analysis to identify patterns and themes in the data supplemented with selected techniques commonly associated with grou...

Metabolic Signatures Associated with COVID-19 Vaccination in Serum from Healthy Individuals

Background: COVID-19 vaccines have proven effective in reducing severe disease and mortality from SARS CoV-2 infection. The underlying molecular mechanisms and alterations in the human serum metabolome influencing the effectiveness and development of immunity remain unclear. Meth...

Digital epidemiology investments, Saudi Arabia.

Problem: Traditional epidemiological surveillance methods are often limited by delays in reporting and fragmented data systems. Saudi Arabia faces additional public health challenges from mass gatherings during Hajj and Umrah, an increasing burden of noncommunicable diseases and...