Ministry of Education

Fatty acid cycling drives metabolic uncoupling and simultaneous nitrogen removal in a low-aeration and no-recirculation activated sludge system

Metabolic uncoupling represents a fundamental strategy for in-situ sludge reduction, yet its underlying metabolic mechanisms under low-aeration conditions remain poorly understood. Here, we investigated activated sludge performance in a reactor with a depth-to-diameter ratio of 4...

Depression and anxiety mediate the association between sleep quality and health-related quality of life in people living with HIV

Sleep disturbances are highly prevalent among people living with HIV (PWH) and frequently co-occur with psychiatric comorbidities such as depression and anxiety. Although these factors independently predict health-related quality of life (HRQoL), the extent to which psychiatric s...

Exploring the potential of large language models for public participation in urban redevelopment planning

Public participation is essential to human-centered urban planning, yet existing approaches often struggle to translate dispersed public opinions into clear and discussable preference expressions. This limits substantive deliberation between public preferences and expert knowledg...

The “Five in One” integrated precise prevention and control system for pollen allergic diseases in Northern China: A narrative review with global perspective

Allergic diseases driven by airborne pollen are a growing public health burden in Northern China, where spring tree pollens and summer–autumn weed pollens are major triggers of allergic rhinitis, asthma, conjunctivitis, atopic dermatitis, and anaphylaxis. Internationally, managem...

Land-use specific spatiotemporal scaling laws of urban vitality dynamics: Evidence from 30 Chinese cities

Urban vitality is a core attribute of livable, attractive, and sustainable cities. Studies have explored the spatiotemporal patterns of urban vitality and scaling laws in urban systems. However, whether scale-invariant vitality dynamics vary systematically across land-use categor...

Bacillus velezensis SGTSH 0811 suppresses sunflower sclerotiniose by pathogen inhibition and host resistance induction

Abstract Sunflower sclerotiniose caused by Sclerotinia sclerotiorum threatens global sunflower production, the complete molecular antagonistic mechanisms of Bacillus velezensis biocontrol strains are still unclear. This study isolated rhizosphere strain SGTSH 0811 from healthy su...

m⁶A-dependent TRIM71 stabilization by YTHDC1 promotes hepatoblastoma progression

Abstract Hepatoblastoma (HB) is the most common primary malignant liver cancer in children. Although complete surgical resection and standardized chemotherapy remain the most effective treatments for HB, they are not curative for all patients. Therefore, a deeper understanding of...

Safety and satisfaction of voluntary medical male circumcision among men who have sex with men in China

PURPOSE: To investigate the safety and satisfaction of circumcision among men who have sex with men (MSM), as voluntary male medical circumcision (VMMC) may be an innovative and acceptable tool for HIV prevention among this population in the future. METHODS: Participants who volu...

Gut microbiota dysbiosis correlates with reduced drug exposure in patients with multidrug-resistant tuberculosis

Although systemic exposure to anti-tuberculosis agents is critical for therapeutic efficacy, substantial inter-individual variability of drug exposure persists despite standardized dosing. Emerging studies suggest that the gut microbiota may influence drug metabolism and host pha...

Adenosine 2A receptor drives microglial efferocytosis to accelerate white matter repair and functional recovery after stroke

Although reperfusion therapy effectively restores blood flow to occluded brain arteries after ischemic stroke, many patients develop persistent white matter injury, a major contributor to long-term neurological disability. Currently, there are few approved clinical therapies that...

LGALS1 promotes gastric cancer progression and is associated with epithelial-mesenchymal transition and tumor immune microenvironment features

Galectin-1 (Gal-1, encoded by LGALS1) has been implicated in malignant progression across multiple cancer types, but its prognostic significance and association with tumor immune microenvironment features in gastric cancer (GC) remain incompletely understood. In this study, we in...