Millennium Institute for Integrative Biology

MPNN-Guided Redesign of PET Hydrolases with Enhanced Catalytic Activity below the PET Glass Transition Temperature

Abstract Enzymatic depolymerization of polyethylene terephthalate (PET) presents a sustainable route for plastic circularity, but its industrial viability is disadvantaged by the need for thermostable enzymes active under mild, energy-efficient conditions. While polyester hydrola...

Genomic detection of highly pathogenic avian influenza H5N1 in Antarctic seabirds reveals connectivity with South American viral lineages

Abstract Emerging avian viruses increasingly threaten Antarctic wildlife, raising concerns about ecosystem health and biodiversity. In this study, we conducted a comprehensive investigation of avian influenza virus (influenza A virus, IAV) in both resident and migratory birds inh...

Subglottic Pressure and Immersion Depth: Key Determinants of Voice Outcomes in Water Resistance Tube Exercise

Purpose: The present study aimed to evaluate the effects of different immersion depth levels and subglottic pressure (P sub ) levels on the oscillatory features of oral pressure (P oral ; frequency, amplitude, and regularity), the degree of glottal adduction, and the subjective p...